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Brief summary: hypothesis, hrt does not increase the risk of lupus activity exacerbation, it is effective for the relief of menopausal symptoms and improves. Immunosuppressive therapy, testosterone replacement therapy can be. Download citation | the effects of hormone replacement therapy on autoimmune disease: rheumatoid arthritis and systemic lupus erythematosus | autoimmune. Click here to subscribe to the lupus news today newsletter. Lower testosterone levels might be the reason behind why women are at a. Do oral contraceptives or hormone replacement therapy increase the. Since the discovery that blocking hormones can slow the growth of cancer cells in the 1960s, androgen deprivation therapy has been the. Trt for hypercoagulable states such as factor v leiden and lupus. Lupus or sle is an autoimmune disorder. Estrogen and testosterone therapy. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. 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